The Invention provides compositions and methods of enhancing the viability of primary stem cells and enhancing the engraftment of transplanted stem cells into a mammalian recipient. Accordingly, the invention includes a method of regenerating a mesenchymally-derived tissue by contacting the tissue with a composition containing an isolated adult mesenchymal stem cell, which are apoptosis-resistant. The mesenchymal stem cell is an adult cell obtained from an adult bone marrow.
申请公布号
WO2004044142(A2)
申请公布日期
2004.05.27
申请号
WO2003US35111
申请日期
2003.11.05
申请人
THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;DZAU, VICTOR, J.;MANGI, ABEEL;IP, JAMES, EDMUND