摘要 |
<p>(I) In the formulae, R1, R2, R3, R4, R5, R6, R7, R8, R9, and A have the same meanings as in the description. A method in which pyradine nucleotide and pyradine nucleoside analogues [2] and [3z] undergo in vivo conversion and are further decomposed and phosphorylated to become a pyradine nucleotide analogue [1b], which has virus proliferation inhibitory activity and/or virucidal activity. The method is useful as a remedy for viral infectious diseases. Also provided is a pyradinecarboxamide analogue or a salt thereof which are useful as a preventive/remedy for viral infectious diseases.</p> |