发明名称 |
PHENYLCARBOXAMIDE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE |
摘要 |
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions i n the prevention or treatment of such diseases in which the beta-secretase enzyme is involved.
|
申请公布号 |
CA2505098(A1) |
申请公布日期 |
2004.05.27 |
申请号 |
CA20032505098 |
申请日期 |
2003.11.06 |
申请人 |
MERCK & CO., INC. |
发明人 |
VACCA, JOSEPH P.;STACHEL, SHAWN J.;COBURN, CRAIG A. |
分类号 |
C07C255/46;C07C255/57;C07C311/08;C07D207/08;C07D211/22;C07D211/32;C07D211/44;C07D211/46;(IPC1-7):C07D207/00;A61K31/40 |
主分类号 |
C07C255/46 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|