ANTISENSE MODULATION OF APOLIPOPROTEIN B EXPRESSION
摘要
Antisense compounds, compositions and methods are provided for modulating the expression of apolipoprotein B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding apolipoprotein B. Methods of using these compounds for modulation of apolipoprotein B expression and for treatment of diseases associated with expression of apolipoprotein B are provided.
申请公布号
WO2004044181(A2)
申请公布日期
2004.05.27
申请号
WO2003US36411
申请日期
2003.11.13
申请人
ISIS PHARMACEUTICALS INC.;CROOKE, ROSANNE;GRAHAM, MARK;LEMONIDIS-TARBET, KRISTINA;DOBIE, KENNETH, W.
发明人
CROOKE, ROSANNE;GRAHAM, MARK;LEMONIDIS-TARBET, KRISTINA;DOBIE, KENNETH, W.