COMPOSITIONS AND METHODS FOR TREATING ACUTE MYELOID LEUKEMIA

摘要

A method of treating acute myeloid leukemia in a mammal in need of such treatment by inhibiting G-CSF activity or reducing G-CSF protein level in the mammal. This may be accomplished, for example, by administering to the mammal an effective amount of an G-CSF antagonist or by inhibiting expression of a G-CSF gene. Compositions and polynucleotide constructs useful in the invention are also disclosed.