发明名称 Dosage form of sodium ibuprofen
摘要 A non effervescent tablet of ibuprofen, comprising a tablet core and, if desired, a sugar or film coat, wherein the tablet core, based on the weight of the tablet core, consists of 50 to 100% by weight sodium ibuprofen hydrate and 50 to 0% by weight auxiliary material component and contains no lubricant and no disintegrant, and wherein the sodium ibuprofen hydrate has a water content of 8 to 16% by weight, preferably 11 to 16% by weight, possesses a sufficient hardness, is comparably small and leads to a particularly rapid increase in blood level and thereby to an accelerated onset of analgesic effect. Contrary to the current doctrine sodium ibuprofen hydrate having a suitable water content is sufficiently compressible.
申请公布号 US2004102522(A1) 申请公布日期 2004.05.27
申请号 US20030683283 申请日期 2003.10.14
申请人 GRUBER PETER;REHER MARKUS 发明人 GRUBER PETER;REHER MARKUS
分类号 A61K9/20;A61K9/28;A61P29/00;(IPC1-7):A61K31/192;A61K9/24 主分类号 A61K9/20
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