| 发明名称 |
Substituted polycyclic aryl and heteroaryl pyrymidinones useful as anticoagulants. |
| 摘要 |
The invention relates to substituted polycyclic aryl and heteroaryl pyrimidinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases. |
| 申请公布号 |
ZA200109339(B) |
申请公布日期 |
2004.05.26 |
| 申请号 |
ZA20010009339 |
申请日期 |
2001.11.13 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
MICHAEL S. SOUTH;WILLIAM NEUMANN;MELVIN L. RUEPPEL;ASHTON T. II HAMME;DARIN E. JONES |
| 分类号 |
C07D253/06;A61K31/513;A61K31/53;A61K45/00;A61P7/02;A61P9/00;A61P9/10;A61P11/00;A61P43/00;C07D239/46;C07D239/47;C07D253/07;C07D401/04;C07D417/12 |
主分类号 |
C07D253/06 |
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