发明名称 |
PULMONARY ADMINSTRATION OF CHEMICALLY MODIFIED INSULIN |
摘要 |
<p>The present inventon provides active, hydrophilic polymer-modified derivatives of insulin. The insulin derivatives of the invention are, in one aspect, suitable for delivery to the lung and exhibit pharmakokinetic and/or pharmacodynamic properties that are significantly improved over native insulin.</p> |
申请公布号 |
LT2003107(A) |
申请公布日期 |
2004.05.25 |
申请号 |
LT20030000107 |
申请日期 |
2003.12.17 |
申请人 |
NEKTAR THERAPEUTICS |
发明人 |
PATTON, JOHN, S.;KUO, MEI, CHANG;HARRIS, MILTON, J.;LEACH, CHESTER;PERKINS, KIMBERLY;BUECHE, BLAINE |
分类号 |
A61K9/08;A61K9/12;A61K9/19;A61K9/24;A61K9/72;A61K38/00;A61K38/16;A61K38/28;A61K47/34;A61K47/48;A61L9/04;A61P3/10;C07K14/62;(IPC1-7):A61L9/04 |
主分类号 |
A61K9/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|