BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS ESTROGEN AGONISTS/ANTAGONISTS

摘要

Compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein at least one of R<1> and R<2> is a group of the formula (II), wherein R<7>, R<8>, R<10> and R<11> are each independently hydrogen; hydroxy; (C1-C6) alkyl; (C1-C6) alkoxy; or halogen; R<9> is hydroxy; (C1-C6) alkoxy; (C1-C6)alkoxycarbonyloxy; (C1-C6)alkylcarbonyloxy; (C3-C8)cycloalkoxy; (C4-C8)cycloalkenyloxy; or (C6-C12) aryloxy; are useful as estrogen agonists and/or antagonists and pharmaceutical uses thereof.