摘要 |
A method for coating a particulate material for pharmaceutical, cosmeceutical, nutriceutical or cosmetic use or for use in food or food stuff, the coating being performed in a coating equipment, which comprises a coating chamber having i) means for supply of a coating composition, and ii) means for supply of inlet air to provide a flow of inlet air, the method comprises (i) loading uncoated or pre-coated particulate material into the coating chamber, (ii) providing a flow of inlet air that has been adjusted so that the humidity of the air in the coating chamber ensures that unwanted agglomeration of the particulate material and/or adherence to the coating equipment are substantially reduced or avoided during the coating process, and (iii) spraying on the particulate material a coating composition comprising a solvent that contains at least about 70% v/v of one or more organic solvents and at the most about 30% v/v of an aqueous medium, to obtain coated particulate material containing at the most about 20% w/w agglomerates. The method is especially suitable in order to enable coating by means of an organic solvent based coating composition and avoids generally observed problems with respect to static electricity, adherence and formation of agglomerates. |
申请人 |
NYCOMED DANMARK APS;BERTELSEN, POUL, EGON;CHRISTENSEN, KARIN, LOEWENSTEIN;NYBO, PERNILLE;DJUURHUS, ANNMARI;SCHLYTER, JIMMY, HIRSCHSPRUNG |
发明人 |
BERTELSEN, POUL, EGON;CHRISTENSEN, KARIN, LOEWENSTEIN;NYBO, PERNILLE;DJUURHUS, ANNMARI;SCHLYTER, JIMMY, HIRSCHSPRUNG |