ANTIGENIC TARGETS OF AUTOIMMUNE SENSORINEURAL HEARING LOSS (AISNHL) AND DEVELOPMENT OF TESTS FRO DIAGNOSIS AND MANAGEMENT OF AISNHL
摘要
This invention relates generally to antigens reactive with autoantibodies associated with autoimmune sensorineural hearing loss (AISNHL), and in particular relates to a novel antigen, Inner Ear Supporting Cell Antigen (IESCA) reactive with autoantibodies associated with autoimmune sensorineural hearing loss (AISNHL), and to methods for the detecting therapeutic outcomes in treatment of AISNHL patients, and to methods of detecting genetic lesions in genes encoding for such antigens.
申请公布号
WO2004041152(A2)
申请公布日期
2004.05.21
申请号
WO2003US14248
申请日期
2003.05.06
申请人
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;CAREY, THOMAS, E.;NAIR, THANKAM, S.;BECKMAN, JENNIFER, GRAY