发明名称 |
FABRICATION OF A HIGH RESOLUTION BIOLOGICAL MOLECULE DETECTION DEVICE WITH GOLD ELECTRICAL CONDUCTORS |
摘要 |
The present invention relates to a method of manufacturing a detection device which involves providing a substrate having a layer of gold and a first layer of photosensitive material. Next, the substrate is subjected to a first level photolithography treatment to produce a gold electrical conductor containing conductive fingers with spaces between them. Finally, biological probes are attached to the conductive fingers under conditions effective to form a gap between the biological probes on the spaced apart conductive fingers. As a result, a target molecule, if present in a sample, can bind to a pair of the biological probes on the spaced apart conductive fingers to bridge the gap between the biological probes, allowing detection of the target molecule. |
申请公布号 |
WO2004042344(A2) |
申请公布日期 |
2004.05.21 |
申请号 |
WO2002US36650 |
申请日期 |
2002.11.14 |
申请人 |
INTEGRATED NANO-TECHNOLOGIES, LLC;PHAM, HONG-AN;CONNOLLY, DENNIS, M. |
发明人 |
PHAM, HONG-AN;CONNOLLY, DENNIS, M. |
分类号 |
C07H21/02;C07H21/04;C12Q1/68;C25D3/04;C25D3/48;C25D5/00;C40B40/06;G01N;G01N33/543;G03C5/00 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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