发明名称 INHIBITORS OF beta-SECRETASE, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE OR MILD COGNITIVE IMPAIRMENT
摘要 One aspect of the present invention relates to urea-containing compounds. In certain embodiments, the urea-containing compounds of the present invention comprise a heteroaromatic moiety. Another aspect of the present invention relates to a method of inhibiting a beta-secretase using a urea-containing compound of the present invention. A third aspect of the present invention relates to a method of treating Alzheimer's Disease or mild cognitive impairment using a urea-containing compound of the present invention.
申请公布号 WO2004041211(A2) 申请公布日期 2004.05.21
申请号 WO2003US35219 申请日期 2003.11.03
申请人 GEORGETOWN UNIVERSITY;KOZIKOWSKI, ALAN, P.;AISEN, PAUL, S.;PETUKHOV, PAVEL 发明人 KOZIKOWSKI, ALAN, P.;AISEN, PAUL, S.;PETUKHOV, PAVEL
分类号 A61K;A61K31/34;A61K31/38;A61K31/40;C07C233/00;C07C275/14;C07C275/16;C07C275/20;C07C275/24;C07D207/10;C07D307/02;C07D307/66;C07D333/36;C07D405/00 主分类号 A61K
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