DOSAGE FORM PROVIDING ASCENDING RELEASE OF LIQUID FORMULATION

摘要

The present invention includes a dosage form that releases a liquid active agent formulation over a period of time at an ascending rate. The dosage form of the present invention includes a capsule or other reservoir capable of containing a liquid active agent formulation, a driving means for expelling the liquid active agent formulation from the capsule over an extended period of time and a rate altering means for increasing the rate at which the driving means expels liquid active agent formulation from the capsule. The present invention also includes a method of manufacturing a controlled release dosage form providing the release of liquid active agent formulation at an ascending rate. The method of the present invention includes providing a capsule or reservoir suitable for containing a liquid active agent formulation, filling the capsule with a liquid active agent formulation, providing the capsule with a driving means for expelling the liquid active agent formulation from the capsule to an environment of use, and providing a rate altering means for increasing the rate at which the driving means expels the liquid active agent formulation.