发明名称 Method for producing a phenothiazine granulate with improved properties
摘要 The invention relates to a method for producing a phenothiazine granulate with a narrow particle size distribution. At least 98% pure phenothiazine in liquid form is pressed through a device provided with boreholes and a frequency is applied to said liquid phenothiazine. The liquid phenothiazine discharged through the boreholes enters a cooling medium having a temperature of between -196 and +120° C. The drops of liquid phenothiazine thus produced are brought to a temperature below melting point and are optionally solidified in another post-cooling area. Optionally, fine-grain particles or coarse-grained particles thus formed can be subsequently removed by appropriate methods. The bulk density of the obtained phenothiazine granulates ranges more particularly from 720-780 kg/m<3>.
申请公布号 US2004094749(A1) 申请公布日期 2004.05.20
申请号 US20030312019 申请日期 2003.08.11
申请人 BEYER J?UUML,RGEN;BREIER DIETMAR;EFFENBERGER GUNTHER;ROOS MICHAEL;RUPPERT JENS;JUST OLAF;WEHLE DETLEF 发明人 BEYER JUERGEN;BREIER DIETMAR;EFFENBERGER GUNTHER;ROOS MICHAEL;RUPPERT JENS;JUST OLAF;WEHLE DETLEF
分类号 C07D279/36;A01N25/12;A01N43/84;A61K31/5415;B01J2/04;C07B63/04;C07D279/00;C08F2/42;C08F20/00;C10M135/36;(IPC1-7):C07D279/00;C10M101/00;C09K15/00 主分类号 C07D279/36
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