| 发明名称 |
Crystal structures of retaining glycosytransferases |
| 摘要 |
The present invention relates to a crystal comprising the ligand binding pocket of a glycosyltransferase enzyme and optionally a donor molecule or analogue thereof and/or an acceptor molecule or analogue thereof. The present invention also relates to the use of such a crystal to identify ligands capable of modulating glycosyltransferase activity, and the use of such ligands in therapeutic applications.
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| 申请公布号 |
US2004096951(A1) |
申请公布日期 |
2004.05.20 |
| 申请号 |
US20030450802 |
申请日期 |
2003.11.17 |
| 申请人 |
WITHERS STEPHEN G.;WAKARCHUK WARREN W.;STRYNADKA NATALIE C.J.;DIECKELMANN MANUELA;LY HOA;PERSSON KARINA |
发明人 |
WITHERS STEPHEN G.;WAKARCHUK WARREN W.;STRYNADKA NATALIE C.J.;DIECKELMANN MANUELA;LY HOA;PERSSON KARINA |
| 分类号 |
C12N9/10;(IPC1-7):C12P19/38;C08B37/00 |
主分类号 |
C12N9/10 |
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