发明名称 |
Polyetherester copolymers as drug delivery matrices |
摘要 |
A composition for delivering a biologically active agent to a host. The composition comprises a product including a biologically active agent encapsulated in a matrix comprising a copolymer, of a polyalkylene glycol and an aromatic polyester, such as a polyethylene glycol terephthalate/polybutylene terephthalate copolymer. The polyether-ester copolymer protects the biologically active agent (including proteins, peptides, and small drug molecules) from degradation or denaturation and provides and essentially zero-order release. |
申请公布号 |
EP1247522(B1) |
申请公布日期 |
2004.05.19 |
申请号 |
EP20020077025 |
申请日期 |
1997.08.18 |
申请人 |
CHIENNA B.V. |
发明人 |
GOEDEMOED, JACOB HILDEBRAND;HENNINK, WILHELMUS EVERHARDUS;BEZEMER, JEROEN MATTIJS;FEIJEN, JAN;VAN BLITTERSWIJK, CLEMENS;DE BRUIJN, JOOST DICK |
分类号 |
A61K9/00;A61K9/16;A61K9/22;A61K47/18;(IPC1-7):A61K9/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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