| 发明名称 |
PEPTIDES FOR THE PREPARATION OF VACCINES AGAINST BORDETELLA PERTUSSIS. |
| 摘要 |
<p>The present invention discloses polypeptides for use in vaccines against pertussis and parapertussis. The polypeptides of the invention are derived from the Bordetella pertussis pertactin. Preferably, the polypeptides of the invention comprise sequences from region 1 of pertactin, in particular they comprise one or more GGFGP or GGAVP repeats. Alternatively the polypeptides of the invention have a pertactin sequence from which part or all of region 1 or region 2 is deleted. The polypeptides of the invention are incorporated in compositions that are useful as vaccines for human and veterinary purposes. The invention further discloses antibodies against the pertactin-derived polypeptides of the invention.</p> |
| 申请公布号 |
MXPA02012664(A) |
申请公布日期 |
2004.05.14 |
| 申请号 |
MX2002PA12664 |
申请日期 |
2001.06.29 |
| 申请人 |
DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR |
发明人 |
MOOI, FREDERIK, ROBERT |
| 分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/002;A61K39/10;A61K39/395;A61P31/04;A61P37/02;C07K14/235;C07K14/325;C07K16/12;C12N15/00;C12N15/31;C12N15/62 |
主分类号 |
C12N15/09 |
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