Tlr/cd14 binding inhibitor

摘要

The present invention provides an anti-CD14 antibody and fragments thereof that have a function of inhibiting the binding between CD14 and Toll Like Receptor (TLR). And also hybridomas producing the antibody or fragments thereof, peptides, method of preparing antibodies, CD14 mutant polypeptide, method of screening medicaments for treating sepsis and pharmaceutical compositions for sepsis were provided.