发明名称 |
HIGH-MOLECULAR WEIGHT DERIVATIVES OF CAMPTOTHECINS |
摘要 |
It is intended to provide water-soluble derivatives of camptothecins which a re excellent in therapeutic effect and suitable for chemotherapy for cancer. Namely, a water-soluble high-molecular weight derivative of camptothencin being excellent in sustained-release which is obtained by ester-bonding carboxylate group of a polyethylene glycol-polycarboxylic acid polymer to phenolic hydroxyl group of phenolic camptothencin.
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申请公布号 |
CA2502870(A1) |
申请公布日期 |
2004.05.13 |
申请号 |
CA20032502870 |
申请日期 |
2003.10.29 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA |
发明人 |
KITAGAWA, MASAYUKI;OKAMOTO, KAZUYA |
分类号 |
A61K31/4745;A61K47/48;A61P35/00;A61P43/00;(IPC1-7):C08G81/00;A61K31/474 |
主分类号 |
A61K31/4745 |
代理机构 |
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主权项 |
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地址 |
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