发明名称 |
Method for studying the effects of commensal microflora on mammalian intestine and treatments of gastrointestinal-associated disease based thereon |
摘要 |
a method of investigating chemical changes resulting from commensal microflora colonisation of mammalian intestine which comprises: a) measuring gene expression in commensal bacterium-colonized and germ-free intestine of at least one gene; and b) identifying a gene from a) that has at least a 2-fold difference in expression level between commensal bacterium-colonized and germ-free intestine. The method selects genes for further evaluation, and gives rise to the development of prophylactic treatments.
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申请公布号 |
US2004091893(A1) |
申请公布日期 |
2004.05.13 |
申请号 |
US20030432819 |
申请日期 |
2003.10.31 |
申请人 |
GORDON JEFFREY;HOOPER LORA VIRGINIA;STAPPENBECK THADDEUS SMITH;FALK PER;HANSSON LENNART |
发明人 |
GORDON JEFFREY;HOOPER LORA VIRGINIA;STAPPENBECK THADDEUS SMITH;FALK PER;HANSSON LENNART |
分类号 |
C12Q1/18;C12Q1/68;G01N33/50;(IPC1-7):C12Q1/68;G01N33/554;G01N33/569 |
主分类号 |
C12Q1/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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