发明名称 METHOD AND APPARATUS FOR PRODUCING CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING
摘要 The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and a catalyst for the hydrogenation of a substrate compound, hydrogenating (110) the substrate with hydrogen gas (H2) enriched in para-hydrogen (p-<1>H2) to form a hydrogenated contrast agent and exposing (120) the contrast agent to a oscillating magnetic field in combination with a stationary magnetic field. The apparatus comprises a magnetic treatment unit (240) equipped with means for producing an oscillating and a stationary magnetic field.
申请公布号 WO2004019995(A3) 申请公布日期 2004.05.13
申请号 WO2003EP09587 申请日期 2003.08.29
申请人 AMERSHAM HEALTH (R & D) AB;GOLDMAN, MAURICE;AXELSSON, OSKAR;JOHANNESSON, HAUKUR;ARDENKJAER-LARSEN, JAN-HENRIK 发明人 GOLDMAN, MAURICE;AXELSSON, OSKAR;JOHANNESSON, HAUKUR;ARDENKJAER-LARSEN, JAN-HENRIK
分类号 A61K49/00;A61K49/06 主分类号 A61K49/00
代理机构 代理人
主权项
地址