METHOD AND APPARATUS FOR PRODUCING CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING
摘要
The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and a catalyst for the hydrogenation of a substrate compound, hydrogenating (110) the substrate with hydrogen gas (H2) enriched in para-hydrogen (p-<1>H2) to form a hydrogenated contrast agent and exposing (120) the contrast agent to a oscillating magnetic field in combination with a stationary magnetic field. The apparatus comprises a magnetic treatment unit (240) equipped with means for producing an oscillating and a stationary magnetic field.
申请公布号
WO2004019995(A3)
申请公布日期
2004.05.13
申请号
WO2003EP09587
申请日期
2003.08.29
申请人
AMERSHAM HEALTH (R & D) AB;GOLDMAN, MAURICE;AXELSSON, OSKAR;JOHANNESSON, HAUKUR;ARDENKJAER-LARSEN, JAN-HENRIK