发明名称 Compositions and methods for inhibiting viral replication
摘要 The present invention relates to a double-stranded ribonucleic acid (dsRNA) having a nucleotide sequence which is less that 30 nucleotides in length and which is substantially identical to at least a part of a 3'-untranslated region (3'-UTR) of a (+) strand RNA virus, such as HCV, as well as pharmaceutical compositions comprising the dsRNA, together with a pharmaceutically acceptable carrier. The pharmaceutical compositions are useful for treating infections and diseases caused by the replication or activity of the (+) strand RNA virus, as well as methods for inhibiting viral replication.
申请公布号 US2004091457(A1) 申请公布日期 2004.05.13
申请号 US20030384512 申请日期 2003.03.07
申请人 RIBOPHARMA AG 发明人 JOHN MATTHIAS;LIMMER STEFAN;VORNLOCHER HANS-PETER;KREUTZER ROLAND
分类号 A61K38/00;A61P35/00;C12N7/01;C12N15/113;(IPC1-7):A61K48/00;C07H21/02 主分类号 A61K38/00
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