发明名称 |
CELLS OF THE CARDIOMYOCYTE LINEAGE PRODUCED FROM HUMAN PLURIPOTENT STEM CELLS |
摘要 |
This invention provides populations human cells of the cardiomyocyte lineage. The cells are obtained by causing cultures of pluripotent stem cells to differentiate in vitro, and then harvesting cells with certain phenotypic features. Differentiated cells bear cell surface and morphologic markers characteristic of cardiomyocytes, and a proportion of them undergo spontaneous periodic contraction. Highly enriched populations of cardiomyocytes and their replicating precursors can be obtained, suitable for use in a variety of applications, such as drug screening and therapy for cardiac disease.
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申请公布号 |
WO03006950(B1) |
申请公布日期 |
2004.05.13 |
申请号 |
WO2002US22245 |
申请日期 |
2002.07.12 |
申请人 |
GERON CORPORATION;XU, CHUNHUI |
发明人 |
XU, CHUNHUI |
分类号 |
C12N15/09;A61K35/12;A61K35/28;A61K35/34;A61P9/00;C12N5/02;C12N5/0735;C12N5/077;C12N5/10;C12Q1/02;(IPC1-7):C12N5/00;C12N5/06 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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