| 摘要 |
Compounds of the formula (I) in which R<1 >is CN, or C(=NH)-NH2, CON(R<3>)2 or [C(R<4>)2]nN(R<3>)2, each of which is unsubstituted or monosubstituted by C(=O)R<3>, COOR<3>, or<3 >or by a conventional amino-protecting group, or W is -NR<3>CO-, -NR<3>COC(R<4>)2, NR<3>C(R<4>)<custom-character file="US20040092517A1-20040513-P00900.TIF" wi="20" he="20" id="custom-character-00001"/>2) or -C(R<4>)2NR<3>C(<4>)2-, X is -C(R<3>)2-, -[C(R<3>)2]2-, -C(R-<3>)2O- or -C(R<3>)2NR<3>, Y is alkylene, cycloalkylene, Het-diyl or Ar-diyl, T is OR<3>, N(R<3>)2, N(R<3>)2CON(R<3>)2, a monocyclic or bicyclic, saturated, unsaturated or aromatic heterocyclic radical having from 1 to 4 N, O and/sor S atoms which is unsubstituted or monosubstituted, disubstituted or trisubstituted, or a phenyl radical which is unsubstituted or monosubstituted, disubstituted or trisubstituted are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic disorders and for the treatment of tumours.
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