发明名称 |
Composition and method of sustaining chemotherapeutic effect while reducing dose of chemotherapeutic agent using cox-2 inhibitor and statin |
摘要 |
The invention proposes the use of a selective COX-2 inhibitor and an HMG-CoA reductase inhibitor (a statin) to sensitize cancer cells or chemotherapy or radiopharmatherapy, and preferably a glutathione pathway enhancing and detoxifying compound such as cystine so that cancerous cells are more easily penetrated while normal cells are protected. Timing of therapy and methods are covered.
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申请公布号 |
US2004092565(A1) |
申请公布日期 |
2004.05.13 |
申请号 |
US20030470032 |
申请日期 |
2003.07.22 |
申请人 |
KINDNESS GEORGE;SCHUMM BROOKE |
发明人 |
KINDNESS GEORGE;SCHUMM BROOKE |
分类号 |
A61K31/195;A61K31/198;A61K31/22;A61K31/225;A61K31/34;A61K31/35;A61K31/355;A61K31/365;A61K31/366;A61K31/385;A61K31/415;A61K33/04;A61K33/38;A61K45/06;(IPC1-7):A61K31/415 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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