发明名称 |
NOVEL VIRUS PROLIFERATION INHIBITION/VIRUCIDAL METHOD AND NOVEL PYRADINE NUCLEOTIDE/PYRADINE NUCLEOSIDE ANALOGUE |
摘要 |
<CHEM> wherein each of R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<8>, R<9> and A has the same meaning as given in the specification. <??>The present invention relates to a method for exhibiting a virus growth-inhibiting effect and/or a virucidal effect, in which pyrazine nucleotide analog Ä2Ü and pyrazine nucleoside analog Ä3zÜ are subjected to biotransformation, decomposed and then phosphorylated, so that they become a pyrazine nucleotide analog Ä1bÜ exhibiting the aforementioned effect. This method is useful as a method for treating virus infections. Moreover, the pyrazine carboxamide analog or a salt thereof of the present invention is useful as an agent for preventing or treating virus infections. |
申请公布号 |
EP1417967(A1) |
申请公布日期 |
2004.05.12 |
申请号 |
EP20020760622 |
申请日期 |
2002.08.13 |
申请人 |
TOYAMA CHEMICAL CO., LTD. |
发明人 |
FURUTA, YOUSUKE;EGAWA, HIROYUKI;TAKAHASHI, KAZUMI;TSUTSUI, YASUHIRO;UEHARA, SAYURI;MURAKAMI, MAKOTO |
分类号 |
A61K31/706;A61K45/00;A61P31/12;C07H19/10;C07H19/20;(IPC1-7):A61K31/706;C12N9/99;C07H19/04 |
主分类号 |
A61K31/706 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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