发明名称 |
SUSTAINED RELEASE MICROPELLETS AND PROCESS FOR PRODUCING THE SAME |
摘要 |
Sustained release micropellets showing a stable controlled-release of a drug without being affected by the changes in pH value etc., characterized by being produced by coating core particles with a layer containing a water-soluble drug and further forming a film layer containing a water-insoluble polymer compound and a plasticizer on the thus obtained particles, locating a water-soluble filler layer between the water soluble drug-containing layer and the film layer, and having an average particle size of 300 mu m or less; medicinal compositions containing these micropellets; and a process for producing the same.
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申请公布号 |
EP1417960(A1) |
申请公布日期 |
2004.05.12 |
申请号 |
EP20020760617 |
申请日期 |
2002.08.12 |
申请人 |
FUJIMOTO CO., LTD. |
发明人 |
YONEDA, FUMIO;HAMANO, FUMIYA;KITANO, EISAKU;HOSONO, TETSUYA |
分类号 |
A61K9/00;A61K9/26;A61K9/50;A61K9/52;A61K31/485;A61K47/38;(IPC1-7):A61K9/52 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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