摘要 |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to new derivatives of benzopyrane and benzoxepine of the formula (I): wherein X, A, R1 and (R)p have values given in cl. 1. Invention relates to methods for their preparing, intermediate compounds and also to pharmaceutical composition comprising compounds of the formula (I) that elicits hypolipidemic and hypoglycemic activity. This provides its using for treatment of dyslipidemia, atherosclerosis and diabetes mellitus. EFFECT: improved preparing method, valuable medicinal properties of compounds and composition. 20 cl, 6 tbl, 30 ex |