| 发明名称 |
Pyrimidine derivatives as IL-8 receptor antagonists |
| 摘要 |
Compounds containing the pyrimidine nucleus and their use to treat diseases and conditions related to inappropriate Interleukin-8 receptor activity are disclosed. The compounds are of the formula I In these compounds, Q is preferably unsubstituted and substituted heterocyclyl; U is usually hydrogen or fluorine; and V is preferably hydrogen, halogen, alkyl, -O-alkyl or -S-alkyl. A representative example is:
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| 申请公布号 |
US2004087601(A1) |
申请公布日期 |
2004.05.06 |
| 申请号 |
US20030340398 |
申请日期 |
2003.01.10 |
| 申请人 |
ERICKSON SHAWN DAVID;BALDWIN JOHN J.;DOLLE ROLAND ELLWOOD;INGLESE JAMES;OHLMEYER MICHAEL H.J.;HO KOC-KAN;BOHNSTEDT ADOLPH C.;KULTGEN STEVEN G.;CONTI PAOLO GIOVANNI MARTINO;LEYSEN DIRK;VAN DER LOUW JAAP |
发明人 |
ERICKSON SHAWN DAVID;BALDWIN JOHN J.;DOLLE ROLAND ELLWOOD;INGLESE JAMES;OHLMEYER MICHAEL H.J.;HO KOC-KAN;BOHNSTEDT ADOLPH C.;KULTGEN STEVEN G.;CONTI PAOLO GIOVANNI MARTINO;LEYSEN DIRK;VAN DER LOUW JAAP |
| 分类号 |
A61P35/00;C07D239/42;C07D239/46;C07D401/04;C07D403/04;C07D405/04;C07D405/12;C07D521/00;(IPC1-7):A61K31/513;C0749/02;C0745/02;C0743/02 |
主分类号 |
A61P35/00 |
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