发明名称 SUSTAINED RELEASE L-ARGININE FORMULATIONS AND METHODS OF MANUFACTURE AND USE
摘要 The present invention provides methods and formulations for the treatment an d prevention of cerebrovascular and cardiovascular diseases and disorders. The present invention is based, at least in part, on the discovery that administering to a subject a formulation comprising an agonist of endothelia l nitric oxide synthase (eNOS), such as an HMG-CoA reductase inhibitor, and a formulation comprising a precursor of NO, such to as L-arginine, may be used to treat or prevent cerebrovascular and/or cardiovascular diseases or disorders.
申请公布号 CA2503284(A1) 申请公布日期 2004.05.06
申请号 CA20032503284 申请日期 2003.10.24
申请人 ENOS PHARMACEUTICAL, INC. 发明人 RON, EYAL S.
分类号 A61K;A61K9/16;A61K9/20;A61K9/22;A61K31/198;A61K31/225;(IPC1-7):A61K9/22 主分类号 A61K
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