发明名称 |
CYCLOOXYGENASE REGULATION WITH PS LIPOSOMES |
摘要 |
<p>A method for treating a COX-2 related disorder comprises administering to a patient pharmaceutically acceptable synthetic, semi-synthetic or natural bodies having a three-dimensional core structure of conformation and size corresponding to mammalian apoptotic cells and/or bodies and expressing or expressible on the surface thereof a ligand selected from, phosphatidylserine, phosphatidylinositol, phosphatidylethanolamine, phosphatidic acid, distearoylphosphatidylserine, dipalmitoylphosphatidylserine, cholesterol, sphingomyelins, or combinations thereof, capable of effectively reducing the COX-2 expression in the mammalian patient.</p> |
申请公布号 |
WO2004037271(A1) |
申请公布日期 |
2004.05.06 |
申请号 |
WO2003CA01631 |
申请日期 |
2003.10.27 |
申请人 |
VASOGEN IRELAND LIMITED;BOLTON, ANTHONY, E.;MANDEL, ARKADY;MORAN, NIAMH |
发明人 |
BOLTON, ANTHONY, E.;MANDEL, ARKADY;MORAN, NIAMH |
分类号 |
A61K9/127;A61K31/415;A61K31/56;A61K31/685;A61P29/00;(IPC1-7):A61K31/685;A61K31/42 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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