METHODS AND APPARATUS FOR INTERACTIVE MICROMANIPULATION OF BIOLOGICAL MATERIALS

摘要

An apparatus for micromanipulating biological materials, comprising: (a) a laser emitting light at a wavelength>600nm; (b) a matrix supporting the biologic material, comprising a light-absorbing material; and (c) a system for focusing light from the source onto specific regions of the matrix. The light absorbing material absorbs the light and coverts it to heat so as to disrupt the matrix and the biological material at the point where the light contacts the matrix. Preferably, the matrix is supported by a carrier to form a bi-layer matrix composite. In another embodiment, the matrix is supported on a support plate having an aperture which is covered, at least in part, by the matrix. In another embodiment, the a matrix is supported by a carrier, wherein at least one of the matrix and the support plate comprises a cell growth modifier.