发明名称 |
COMPOSITE NANOSPHERES AND THEIR CONJUGATES WITH BIOMOLECULES |
摘要 |
<p>The invention concerns composite nanospheres having a diameter ranging between about 50 and 1000 nm plus or minus 5%, preferably between about 100 and 500 nm plus or minus 5% and advantageously between 100 and 200 nm plus or minus 5%, and comprising an essentially liquid core consisting of an organic phase and inorganic nanoparticles, distributed inside the organic phase, and a skin consisting of at least a hydrophilic polymer derived from the polymerisation of at least one water soluble monomer, in particular N-alkylacrylamide or a N-N-dialkylacrylamide; conjugates derived from said nanospheres; their preparation methods and their uses.</p> |
申请公布号 |
EP1226438(B1) |
申请公布日期 |
2004.05.06 |
申请号 |
EP20000974662 |
申请日期 |
2000.11.06 |
申请人 |
BIO MERIEUX;CENTRE NAT RECH SCIENT |
发明人 |
ELAISSARI ABDELHAMID;BOSC ERIC;PICHOT CHRISTIAN;MANDRAND BERNARD;BIBETTE JEROME;MONDAIN-MONVAL OLIVIER |
分类号 |
G01N33/545;A61K9/51;A61K31/7088;A61K45/00;A61K47/02;A61K47/04;A61K47/32;A61K47/48;A61K48/00;A61P43/00;C09D11/00;G01N33/543;(IPC1-7):G01N33/543;G01N33/546 |
主分类号 |
G01N33/545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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