COMBINATION OF MTOR INHIBITOR AND A TYROSINE KINASE INHIBITOR FOR THE TREATMENT OF NEOPLASMS
摘要
The invention features methods and compositions including an mTOR inhibitor and a tyrosine kinase inhibitor for reducing the proliferation of and enhancing the apoptosis of neoplastic cells. The addition of an MEK inhibitor to this combination further enhances the effectiveness of this therapeutic method.
申请公布号
WO2004004644(A3)
申请公布日期
2004.05.06
申请号
WO2003US20972
申请日期
2003.07.03
申请人
BETH ISRAEL DEACONESS MEDICAL CENTER;NEEL, BENJAMIN, G.;MOHI, GOLAM