发明名称 |
Substituted benz-azoles and methods of their use as inhibitors of Raf kinase |
摘要 |
New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
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申请公布号 |
US2004087626(A1) |
申请公布日期 |
2004.05.06 |
申请号 |
US20030405945 |
申请日期 |
2003.03.31 |
申请人 |
RENHOWE PAUL A.;RAMURTHY SAVITHRI;AMIRI PAYMAN;LEVINE BARRY HASKELL;POON DANIEL J.;SUBRAMANIAN SKARADHA;SUNG LEONARD;FANTL WENDY |
发明人 |
RENHOWE PAUL A.;RAMURTHY SAVITHRI;AMIRI PAYMAN;LEVINE BARRY HASKELL;POON DANIEL J.;SUBRAMANIAN SKARADHA;SUNG LEONARD;FANTL WENDY |
分类号 |
A61K31/4439;A61K31/444;A61K31/4545;A61K31/46;A61K31/4725;A61K31/496;A61K31/506;A61K31/5377;A61K31/55;A61K31/551;A61K45/00;A61P35/00;A61P43/00;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/14;C07D413/04;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D451/14;C07D453/02;(IPC1-7):A61K31/443;A61K31/428;A61K31/423;C07D277/82;C07D263/60;C07D417/02;C07D413/02 |
主分类号 |
A61K31/4439 |
代理机构 |
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代理人 |
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