Microbiological method for producing ascorbic acid

摘要

There is provided a microbiological one-step method for the manufacture of ascorbic acid. The method comprises use of the operon expressing 2-ketogluconate dehydrogenase in naturally occurring microorganisms and microorganisms transformed with DNA encoding the 2-ketogluconate dehydrogenase gene. Ascorbic acid is obtained from culturing microorganisms expressing 2-ketogluconate dehydrogenase.