发明名称 |
(PYRIDINYL AND PYRIMIDYL) TRIENOIC ACID DERIVATIVES AS RETINOID X RECEPTOR MODULATORS. |
摘要 |
<p>The present invention relates to a method of modulating retinoid X receptor activity in a mammal, novel compounds and pharmaceutical compositions for modulating retinoid X receptor activity in a mammal, and methods of making compounds that modulate retinoid X receptor activity in a mammal. The compounds are represented by Structural Formula I: The compounds of Structural Formula I are efficacious insulin sensitizers and do not have the undesirable side effects of increasing triglycerides or suppressing the thyroid hormone axis.</p> |
申请公布号 |
MXPA04000613(A) |
申请公布日期 |
2004.05.05 |
申请号 |
MX2004PA00613 |
申请日期 |
2002.07.18 |
申请人 |
LIGAND PHARMACEUTICALS, INC. |
发明人 |
MARCUS F. BOEHM. |
分类号 |
A61K31/4412;A61P3/00;A61P3/04;A61P3/10;A61P9/10;A61P17/02;A61P17/06;A61P17/14;A61P17/16;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D213/65;(IPC1-7):A61K31/44;C07D239/34;A61K31/513 |
主分类号 |
A61K31/4412 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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