发明名称 LIPID PHOSPHATE PHOSPHATASES AND USES THEREOF FOR TREATING NEURONAL DISEASES
摘要 An isolated protein (I) e.g., lipid phosphatase protein comprising the same or substantially the same amino acid sequence chosen from a fully defined sequence (S1)-(S5) of 763, 746, 766, 716 and 766 amino acids as given in the specification, a splice variant or its salt, is new. Independent claims are also included for: (1) a nucleic acid (II) which comprises at least one nucleic acid encoding (I); (2) a nucleic acid (III) complementary to (II); (3) a vector (IV) comprising (I), (II) and/or (III); (4) an isolated cell (V) comprising (I), (II), (III) or (IV); (5) a transgenic non-human animal (VI) generated from (V); (6) an antibody (VII) directed against (I); (7) producing (I), (II), or (III) involves cultivating (V) and isolating (I), (II) or (III); and (8) a pharmaceutical composition (VIII) for the treatment of neuronal injuries or diseases, comprising (I), (II), (III), (IV), (VI), (VII), a binding compound isolated by using (I), (II) or (III) and/or a functional interactor isolated by using (I), (II) or (III) and if needed suitable auxiliary substances and/or additives. ACTIVITY : Nootropic; Neuroprotective; Cerebroprotective. No biological data given. MECHANISM OF ACTION : None given.
申请公布号 AU2003298080(A1) 申请公布日期 2004.05.04
申请号 AU20030298080 申请日期 2003.09.15
申请人 CHARITE - UNIVERSITATSMEDIZIN BERLIN 发明人 NICOLAI, E. SAVASKAN;ROBERT NITSCH;OLAF NINNEMANN;ANJA, U. BRAUER
分类号 A01K67/027;A61K31/7088;A61K38/00;A61K38/17;A61K39/395;A61P25/28;C07K16/40;C12N1/21;C12N5/10;C12N9/16;C12N15/52;C12Q1/68;G01N33/68 主分类号 A01K67/027
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