发明名称 PYRROLIDINYL- AND PYRROLINYLETHYLAMINE DERIVATIVES AS KAPPA-AGONISTS
摘要 <p>The invention relates to a compound with the formula and to its salt. In the formula A is hydrogen, halogen, hydroxy or similar; the punctured line is optionally a double bond provided that if the punctured line is a double bond then A is absent; Ar1 is phenyl optionally substituted, or similar; Ar2 is aryl or heteroaryl selected amongst phenyl, naphthyl, pyridyl and similar, the aryl or the heteroaryl being optionally substituted; R1 is hydrogen, hydroxy, C1-C4-alkyl or similar; R2 & R3, separately, are selected amongst optionally substituted C1-C7-alkyl, C3-C6-cycloalkyl, C2-C6-alkenyl, C2-C6-alkynyl and similar, or R2 and R3, together with the nitrogen atom to which they are bound, optionally form substituted pyrrolidine, piperidine or morpholine ring. 14 claims</p>
申请公布号 BG64194(B1) 申请公布日期 2004.04.30
申请号 BG19990103239 申请日期 1999.03.11
申请人 PFIZER INC. 发明人 ITO, FUMITAKA;KONDO, HIROSHI
分类号 A61P25/04;A61K31/40;A61K31/4015;A61K31/4025;A61K31/4035;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4439;A61K31/5377;A61P1/06;A61P19/02;A61P23/00;A61P25/00;A61P25/28;A61P29/00;A61P43/00;C07C237/30;C07C239/18;C07D;C07D207/10;C07D207/12;C07D207/20;C07D207/24;C07D213/81;C07D213/82;C07D333/40;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07F7/18;(IPC1-7):C07D207/12;C07C237/44;C07C237/32;C07D295/08;C07D295/12;C07D207/22 主分类号 A61P25/04
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