TRADE molecules and uses related thereto

摘要

Disclosed are methods of modulating proliferation and apoptotic state of cells using agents that modulate the expression and/or activity of TRADE family polypeptides. In particular, two extracellular regions of members of the TRADE family of polypeptides are disclosed as useful in such methods. These methods and polypeptides are particularly useful where the cells are carcinoma or adenocarcinoma cells.