发明名称 |
PHARMACEUTICAL COMPOSITION AND MEDICAL TREATMENTS COMPRISING NOTCH LIGAND PROTEINS |
摘要 |
Provided is a Notch ligand protein or polypeptide comprising a Notch ligand DSL domain; 1 to 5 (but no more than 5) Notch ligand EGF repeat domains; optionally, all or part of a Notch ligand N-terminal domain; and optionally, one or more heterologous amino acid sequences. Also provided is a homogeneous or heterogeneous multimer of the protein or polypeptide and a polynucleotide encoding the Notch ligand protein or polypeptide. An immune response can be modified in a subject by administering the Notch ligand protein or polypeptide to the subject. |
申请公布号 |
AU2003267563(A1) |
申请公布日期 |
2004.04.30 |
申请号 |
AU20030267563 |
申请日期 |
2003.09.09 |
申请人 |
LORANTIS LIMITED |
发明人 |
TAMARA TUGAL;BRIAN, ROBERT CHAMPION;ANDREW, CHRISTOPHER LENNARD;GRAHAME, JAMES MCKENZIE |
分类号 |
A61K31/7088;A61K38/00;A61K38/17;A61K39/00;A61K39/395;A61K48/00;C07H21/04;C07K14/705;C07K19/00;C12N15/09;C12N15/12;C12P21/06 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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