| 发明名称 |
DEMETHYLATED AND/OR OXIDIZED MEMBRANE DNA AND USE THEREOF IN THE DIAGNOSTIC OF AUTOIMMUNE DISEASES |
| 摘要 |
<p>A process for the preparation of oxidized and/or demethylated antigens comprising the steps of: treating a cell with a stress factor selected from the group consisting of UV-radiation, oxidizing reagents, heavy metal salts, drugs, nucleoside and nucleotide analogs, and enzyme inhibitors; lyses of the cell to give a cell lysate; purification of oxidized and/or demethylated antigens from the cell lysate.</p> |
| 申请公布号 |
WO2004036219(A1) |
申请公布日期 |
2004.04.29 |
| 申请号 |
WO2003EP11293 |
申请日期 |
2003.10.13 |
| 申请人 |
BIOTECH TOOLS S.A.;LEGON, THIERRY;HENOT, FREDERIC;QUESTIAUX, NADINE |
发明人 |
LEGON, THIERRY;HENOT, FREDERIC;QUESTIAUX, NADINE |
| 分类号 |
C07H21/00;C07H21/04;C12N15/10;C12N15/11;C12Q1/68;G01N33/564;(IPC1-7):G01N33/564 |
主分类号 |
C07H21/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
