发明名称 ADENOVIRUS EXPRESSING GENES IN REVERSE ORDER AND USE THEREOF
摘要 The invention relates to an adenovirus expressing a first protein which is selected among the group comprising an E1B protein and an E4 protein prior to a second protein that is selected among the group comprising an E1A protein, i.e. the order in which adenoviral genes are expressed is reversed. Said virus is used for the production of a medicament or for replication in cells. The inventive medicament is suitable especially for treating tumors that are multiresistant to cytostatic agents.
申请公布号 WO2004035616(A2) 申请公布日期 2004.04.29
申请号 WO2003EP11427 申请日期 2003.10.15
申请人 HOLM, PER, SONNE 发明人 HOLM, PER, SONNE
分类号 A61K35/76;A61K48/00;A61P35/00;C07K14/005;C12N7/01;C12N15/861 主分类号 A61K35/76
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