| 发明名称 |
Novel inhibitors of IMPDH enzyme |
| 摘要 |
The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5'-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as transplant rejection and autoimmune diseases.
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| 申请公布号 |
US2004082562(A1) |
申请公布日期 |
2004.04.29 |
| 申请号 |
US20030465425 |
申请日期 |
2003.06.19 |
| 申请人 |
GU HENRY H.;DHAR T.G. MURALI;IWANOWICZ EDWIN J. |
发明人 |
GU HENRY H.;DHAR T.G. MURALI;IWANOWICZ EDWIN J. |
| 分类号 |
A61K31/421;A61K31/422;A61K31/427;A61K31/4439;A61K31/4709;A61K31/5377;A61K45/00;A61P29/00;A61P31/12;A61P35/00;A61P37/02;A61P43/00;C07D263/32;C07D307/20;C07D413/12;C07D413/14;C07D417/12;C07D471/04;(IPC1-7):A61K31/541;A61K31/537;A61K31/496;A61K31/454;C07D417/02;C07D413/02 |
主分类号 |
A61K31/421 |
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