Process for detecting increased risk of fetal chromosomal abnormality

摘要

An increased risk of a fetal chromosomal abnormality, for example, fetal Down syndrome can be detected by separating or discriminating alpha-fetoproteins present in the body fluid of a pregnant woman, and measuring the proportion of one or more of the alpha-fetoproteins which have a specific sugar chain structure, relative to the total alpha-fetoproteins.