发明名称 |
Methods for treatment of diabetes using peptide analogues of insulin |
摘要 |
The present invention is directed toward peptide analogues of insulin B chain that are generally derived from peptides comprising residues 9 to 23 of the native B chain sequence. The analogues are altered from the native sequence at position 12, 13, 15 and/or 16, and may be additionally be altered at position 19 and/or other positions. Pharmaceutical compositions containing these peptide analogues are provided. The peptide analogues are useful for treating and inhibiting the development of diabetes.
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申请公布号 |
US2004082503(A1) |
申请公布日期 |
2004.04.29 |
申请号 |
US20030339160 |
申请日期 |
2003.01.08 |
申请人 |
NEUROCRINE BIOSCIENCES, INC. |
发明人 |
GAUR AMITABH;LING NICHOLAS;CONLON PAUL J. |
分类号 |
A61K38/00;C07K14/62;(IPC1-7):A61K38/28 |
主分类号 |
A61K38/00 |
代理机构 |
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地址 |
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