| 发明名称 |
CYANO-SUBSTITUTED DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USE TO TREAT DISEASES |
| 摘要 |
The present invention provides compounds of formula (I), formula (I) and pharmaceutically acceptable salts thereof. The formula I compounds induce mitotic arrest thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inducing mitotic arrest.
|
| 申请公布号 |
WO02079169(A8) |
申请公布日期 |
2004.04.29 |
| 申请号 |
WO2002US09494 |
申请日期 |
2002.03.26 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;LOMBARDO, LOUIS, J.;WU, LAURENCE, I |
发明人 |
LOMBARDO, LOUIS, J.;WU, LAURENCE, I |
| 分类号 |
C07D239/42;A61K31/505;A61K31/506;A61K31/513;A61K45/00;A61P1/04;A61P1/16;A61P9/00;A61P9/06;A61P9/10;A61P9/14;A61P13/12;A61P17/06;A61P19/00;A61P19/02;A61P21/00;A61P21/04;A61P25/14;A61P25/16;A61P25/28;A61P27/16;A61P29/00;A61P35/00;A61P35/02;A61P37/06;C07D211/90;C07D239/22;C07D401/04;C07D401/10;C07D403/10;C07D403/12;C07D405/04;C07D409/04;C07D409/06;C07D409/10;C07D409/12;C07D413/04;C07D413/10;C07D417/04;(IPC1-7):C07D239/42 |
主分类号 |
C07D239/42 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
