| 摘要 |
Tropolone derivatives represented by the formula (I), which have retinoid actions and are useful as active ingredients of medicaments [R<1 >to R<4 >represent hydrogen atom, an alkyl group, or an alkoxyl group; the ring represented by Ar represents an aryl ring or a heteroaryl ring; X represents a single bond, -N=N-, -CON(R<5>)-, -(C=C)nCON(R<6>)-, -N(R<7>)CON(R<8>)-, -SO2N(R<9>)-, -N(R<10>)- (R<5 >to R<9 >represent hydrogen atom or an alkyl group, n represents 1 to 3, R<10 >represents hydrogen atom, an alkyl group, or an acyl group), an alkylene group, an aryldiyl group, or a heterocyclic diyl group; Y represents hydrogen atom, -OR<11 >(R<11 >represents hydrogen atom, an alkyl group, or an acyl group), -NHR<12 >(R<12 >represents hydrogen atom, an alkyl group, an acyl group, or amino group), or a halogen atom.
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