Process for the preparation of 1,3-dihalo substituted benzene derivatives

摘要

Production of 1,3-dihalobenzene derivatives (II) comprises gradually adding a 2,6-dihalobenzaldehyde derivative (I) to alkaline medium or gradually adding the alkaline medium to (I). Production of 1,3-dihalobenzene derivatives of formula (II) comprises gradually adding a 2,6-dihalobenzaldehyde derivative (I) to alkaline medium or gradually adding the alkaline medium to (I). X1, X2 = F, Cl or Br, and R1-R3 = H, halo, OH, 1-12C alkyl, CF3, CHO, 6-14C aryl, alkoxy, aryloxy or NO2.